7 days
Capital and two southern-border cities
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Day 1–3
Asunción
Start in the capital, the largest city on this list with 462,241 people. Settle in, get Paraguayan guaraní cash, and listen for both Guarani and Spanish on the street.
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Day 4–5
Encarnación
Move on to Encarnación, a city of 106,842 people. It is much smaller than the capital, so plan slower days and explore the centre on foot at your own pace.
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Day 6–7
Ciudad del Este
End in Ciudad del Este, home to 350,000 people. Keep your last day free for the trip home. None of these cities is on the coast, so don't plan a beach break.