7 days
Madrid to Andalusia in a Week
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Day 1–3
Start in the capital. Spend a morning at the Prado Museum, which takes 2–3 hours, then explore the old town. May, September, October and April are the best months to visit.
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Day 4
Visit the Mosque-Cathedral of Córdoba, a 1–2 hour stop. Córdoba is at its best in February, October, November or April.
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Day 5–6
See Plaza de España and the old town, a half-day outing. Sevilla's best months are February, April, November and October.
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Day 7
Spend your last day at the Alhambra, which takes about half a day to see properly. May, October, April and November are the recommended months here.